Girls with autism are nearly three times as likely as boys with the disorder to have severe epilepsy that responds poorly to medication1.
The findings, published 26 June in Autism Research, add a twist to one of the biggest conundrums in autism: its 4-to-1 ratio of boys to girls. Research suggests that girls are somehow protected from autism-linked mutations. The new study hints that these mutations also lead to treatment-resistant epilepsy.
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